Cheng Fly Lab @LabFly
We are interested in how nutrient, and metabolism affects stem cells and tumours chengflylab.com Melbourne, Australia Joined August 2018-
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Cheng Fly Lab retweeted
🧠 New research shows the blood–brain barrier helps control #braintumour growth. Led by Prof Louise Cheng in @LabFly , the study finds glial “gatekeeper” cells and a protein called Path influence how #cancer respond to low nutrients. Read more: petermac.org/about-us/news-…
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Cheng Fly Lab retweeted
Come and join us! We are looking for a bioinformatician to join the lab. Work with single cell, multiome and spatial data from model systems and human samples! Our focus is lymphatics and blood brain barrier in development, regeneration and cancer. seek.com.au/job/79558172
Congratulations @khanh_ng97 on the ECR publication prize @AusFly2024 for elifesciences.org/articles/96876
@Fumiaki1984 @HarveyHippoLab @SHCrossman Great having you in Melbourne, what a nice time we had with you and @Hina_kosakamoto
Cheng Fly Lab retweeted
Our latest from @TheCrick … Sebastian Sorge led on this amazing new chemically defined (holidic) diet for fast larval growth & development in Drosophila. It’s called HoldFast, soon to be available to the community, in powdered form, from @VDRC_flies. biorxiv.org/content/10.110… 
It was a privilege to appear on @RRR to talk about our research and discuss what patients should know about cancer cachexia - a metabolic wasting disease affecting cancer patient outcomes. Grateful to our consumer Sudhir Sakhuja and my clinical collaborator @HyunKoMD.
"Cancer cachexia" affects 30% of cancer patients - 80% for advanced cancers - and yet few have heard of the term. Assoc Prof Louise Cheng (@LabFly), @HyunKoMD and cancer survivor Sudhir, have explained this muscle wasting condition to @3RRRFM. Listen: rrr.org.au/shared/broadca…
Cheng Fly Lab retweeted
Paper is out! Astrocytes control quiescent NSC reactivation via GPCR signaling–mediated F-actin remodeling | Sci Adv science.org/doi/10.1126/sc… Kudos to super talented lab members @LukeKunYangLin1 @mahekta @jiaen_lin @GaoYang43766353 and wonderful collaborators @Yusuke_Toyama & Tony
Cheng Fly Lab retweeted
We are excited to announce the next Workshop on Neural Circuits & Behavior of Drosophila that will be held at the Orthodox Academy of Crete (OAC), Kolymbari, from June 15-21, 2025. Please RT.
Cheng Fly Lab retweeted
Missing our @FlyJedi meetings? The #JEDI are back for great #Drosophila science! Follow us for more news and dates! #thereturnofthejedi
Cheng Fly Lab retweeted
Very excited to share our #preprint in @biorxivpreprint in which we found that the transcription factors of JNK and Hippo pathways control epithelial integrity by regulating an overlapping transcriptome 🧵1/10
The JNK and Hippo pathways control epithelial integrity and prevent tumour initiation by regulating an overlapping transcriptome biorxiv.org/cgi/content/sh… #bioRxiv
As the Drosophila OL shares a similar mode of division with mammalian neurogenesis, understanding when and how these progenitors cease proliferation during development can have important implications for mammalian brain size determination and regulation of its overall function.
Happy to share the latest work from the lab, led by our PhD student Khanh Nguyen @khanh_ng97 doi.org/10.7554/eLife.… @eLife
@jpvincentlab @AlexGouldLab @epiddin @OttolineLeyser Congratulations JP!
@BenjaminHogan13 @vascularbiology @PeterMacRes @UniMelbMDHS Congratulations Ben, loved your lab’s gift to you! Congratulations to the lab too.
Cheng Fly Lab retweeted
@LabFly @VeenKellie @unimelb Amazing work by @VeenKellie and great collaboration with @Theo_BrainC_lab and @AaronKrylov .
We thank the reviewers @ReviewCommons for expert reviews, fast turn-around and great suggestions.
As muscle ECM proteins are mostly fat body-derived, the retention of ECM proteins in the fat body causes a reduction in muscle ECM, which results in muscle detachment during cancer cachexia.
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