Mischel Lab @mischellab
The Mischel lab studies extrachromosomal oncogene amplification and altered metabolism in cancer. Account managed by lab members. Retweets are not endorsement. paulmischellab.org Stanford, CA Joined November 2019-
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The eDyNAmiC team will investigate #ecDNA, found in around a third of cancers, hoping to develop much needed treatments for people whose cancer is driven in this way Congratulations Paul Mischel (@mischellab @StanfordMed) and the team, funded by @CR_UK and @theNCI 3/n
It is very exciting to be part of the eDyNAmiC team to take the #CancerGrandChallenges and trackle cancer evolution driven by ecDNA. Thanks for the big support of @CancerGrand @QMULMaths @QMBCI
We are excited to share that the eDyNAmiC team has been chosen as a @CancerGrand, @theNCI & @CR_UK winner! #CancerGrandChallenges
Looking forward to working with @anton_gh, @michelle_monje, @huang_weini, @MariamJHanjani, @SihanSean, @BenjaminWerner_, @HowardYChang, @cbailey_58, @VineetBafna3, and many others.
We are excited to share that the eDyNAmiC team has been chosen as a @CancerGrand, @theNCI & @CR_UK winner! #CancerGrandChallenges
We are honored, grateful for the opportunity, and committed to working together to make a difference for patients with ecDNA-driven cancers. It is a thrill to work with such an amazing group of colleagues.
@CancerGrand @theNCI @CR_UK The team, composed of investigators from 11 institutions across the US, UK, and Germany, will leverage our interdisciplinary expertise to tackle the questions of origin, function, and evolution of ecDNA in cancer.
We are excited to share that the eDyNAmiC team has been chosen as a @CancerGrand, @theNCI & @CR_UK winner! #CancerGrandChallenges
Extrachromosomal DNA (ecDNA) are small rings of DNA that help tumours evolve and evade treatment. The eDyNAmiC team will look at ways to interfere with ecDNA, slow down tumour development & ultimately bring hope to patients whose cancers have become resistant to treatment. 4/6
Congratulations to @kinglhung, @KatieEYost, @HowardYChang and colleagues on this landmark discovery published today in @Nature. We are thrilled to have worked together with you on this.
Our paper is out in @Nature! Extrachromosomal DNA molecules huddle together in cancer cells to activate oncogene expression (which we call ecDNA hubs). A great collaboration with @KatieEYost, @HowardYChang, @549nm, Zhe Liu, and others. (1/10) nature.com/articles/s4158…
Congrats to my former colleague Junfeng Bi @mischellab for the new paper! He found that GBM, the most lethal brain tumor, is sensitive to SMPD1 inhibition. Adding antidepressant fluoxetine to standard-of-care chemotherapy can improve patient survival. cell.com/cell-reports/f…
The idea that a safe, inexpensive, and highly brain penetrant drug could make a difference for glioblastoma patients is exciting, compelling, and needs to be further studied! #Glioblastoma #CancerResearch #Cancer
The team found that GBMs are sensitive to SMPD1 inhibition and that fluoxetine can safely and potently shrink GBM tumors in mice. We also used real world data to identify that addition of fluoxetine to standard of care improves patient survival.
Congratulations to postdoc Junfeng Bi on his new paper out today in @CellReports! It has important mechanistic and clinical implications for glioblastoma patients, spanning from fundamental biology, to clinical data. @Stanford_ChEMH @StanfordPath cell.com/cell-reports/f…
We are thrilled to join the wonderful @Stanford_ChEMH community to continue our research into extrachromosomal DNA!
We are delighted to welcome extrachromosomal DNA pioneer Paul Mischel @mischellab to ChEM-H! Mischel spoke to us about looking where the light isn’t being shone and how genetic SpaghettiOs give cancers an advantage: stanford.io/3ii7BJj @StanfordPath @StanfordMed
Excited to see this paper out. Joint work led by the @CalifanoMd and @VineetBafna3 labs. We characterized frequent human-HPV hybrid circular extrachromosomal DNA #ecDNA in HPV+ oropharyngeal cancer patients. clincancerres.aacrjournals.org/content/early/…
In uveal melanoma, PRC1 loss leads to gene de-repression, chromosome segregation errors, CIN, rupture-prone micronuclei & release of dsDNA into the cytosol, which activates the cGAS-STING pathway to induce inflammatory signalling & confers a poor prognosis nature.com/articles/s4146…
(1/2) Insights from #scRNAseq, coupled with fundamental #cell_biology, reveals loss of #PRC1 in a subset of tumor cells underlies transition of #uveal #melanoma from indolent to #metastatic phenotype. nature.com/articles/s4146… A team effort with @Samuel_Bakhoum @mischellab
This collaborative work was led by @MathieuBakhoum, an alumni of our lab and now a physician scientist @Yale with @LaughneyLab @WeillCornell and @Samuel_Bakhoum @sloan_kettering #Cancer #Melanoma
Congratulations to @MathieuBakhoum on the new paper, which has significant clinical implications for uveal #Melanoma patients, published in @NatureComms. This work functionally links two hallmarks of cancer #epigenetic dysregulation and chromosomal instability. #cancerresearch
Uveal #Melanoma can metastasize. But why do these highly lethal metastases occur in some patients but not others? In our new paper @NatureComms we describe a novel and unanticipated mechanism. #epigenetics @YaleMed @LaughneyLab @Samuel_Bakhoum @mischellab nature.com/articles/s4146…
We are thrilled to announce that @MathieuBakhoum joined @YaleMed as Assistant Professor. Congratulations Mathieu and best wishes on your next and exciting endeavor @Yale! His lab is recruiting! Apply if you are interested in #melanoma and #epigenetics bakhoumlab.org
Delighted to announce that I joined @YaleMed as Assistant Professor in @YaleOph. My laboratory will focus on two research areas with direct clinical applications. #AcademicTwitter #ophthotwitter #Ophthalmology #retina bakhoumlab.org 1/4
Thankful for the outstanding mentorship I received from Paul Mischel @mischellab and colleagues @UCSDHealth. And looking forward to making new friendships and collaborations @Yale. New Haven, here we come! 4/4
Very honored that our grant proposal on #ecDNA in cancer is shortlisted for the #CancerGrandChallenges prize! Grateful to the @CancerGrand. Thank you to all of our team members! And Looking forward to the exciting work ahead.
BREAKING NEWS: today we announce 11 teams selected to compete for our awards! Winners receive up to £20m each and the freedom to unleash their scientific creativity, conducting research that transcends geography and discipline - bit.ly/3cFyrZa #CancerGrandChallenges
Michelle Monje 🟦 @michelle_monje
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Itai Yanai @ItaiYanai
34K Followers 2K Following Professor at the NYU School of Medicine. Co-host of the 'Night Science Podcast' @nightsciencepod and Co-founder of the Night Science Institute https://t.co/lede3rBmXU
King L Hung @kinglhung
1K Followers 157 Following Biologist at Scripps, PhD at Stanford. Dynamics of genomes and cells.
Mariella Filbin @FilbinMariella
4K Followers 611 Following pediatric neurooncologist and physician scientist, passionate about finding new treatments for pediatric brain cancer @dfbc_pedcare @danafarber @bostonchildrens
Dan Landau @landau_lab
12K Followers 3K Following Somatic evolution, cancer genomics, epigenomics (Weill Cornell/New York Genome Center). Hemato-oncologist (NYP). Discl.: https://t.co/7TBNcbcVCP
Elizabeth McKenna @ElizSMcKenna
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Craig Horbinski @CraigHorbinski
13K Followers 3K Following Chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic Florida. My #NIH-funded laboratory studies #glioma and #meningioma.
Anirban Maitra @Aiims1742
33K Followers 3K Following Pancreatic cancer researcher, GI pathologist, husband, dad. Striving to improve the lives of patients with cancer. 🇺🇸 🇮🇳
Jason Sheltzer @JSheltzer
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Nature Genetics @NatureGenet
127K Followers 1K Following Nature Genetics is a monthly journal publishing high impact research in genetics and genomics. RT/like=interesting/relevant, not necessarily endorsement.
Anton Henssen @anton_gh
1K Followers 1K Following Head of preclinical pediatric cancer research @ChariteBerlin ECRC @MDC_Berlin. Extrachromosomal DNA (ecDNA) in cancer. Cancer Grand Challenges Team eDyNAmiC
Harmit S. Malik @HarmitMalik
43K Followers 7K Following Study genetic conflicts professionally. Try to avoid conflicts in personal life (with mixed results). @HutchBasicSci @fredhutch @HHMINEWS He/him
Long Lab @longlabstanford
3K Followers 928 Following Affiliated with @StanfordPath and @Stanford_ChemH. We study mammalian energy metabolism!
Ash Alizadeh, MD/PhD ... @AshAlizadeh
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ZZ Zhao Zhang @zz_zhaozhang
1K Followers 627 Following Associate Professor @DukeU (Tortured by #transposons, #ecDNA, and two toddler boys, but still deeply love them)
Vennetilab @vennetilab
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Julien Sage @SageJulien
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Samuel Bakhoum @Samuel_Bakhoum
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Jian Xu @JianXuLab
3K Followers 1K Following We are a group of scientists & physicians passionate about #epigenetics #metabolism #genomics #leukemia #hematopoiesis #erythropoiesis #cancer #stemcells
Jin-Ho Lee @JinHoMLee
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Zexiang (Brady) Han @zexianghan
78 Followers 240 Following PhD candidate @Cambridge_Uni @KnowleslabCamb | @ImpMaterials alum 🌈 nanomaterials, chiroptics, self-assembly, protein phase transitions, bio/nano interface
Raffaele Colombo @raffcolo
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Robert Bjarnason @robertbjarnason
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Promita Ghosh @ghoshonthemove
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josh Lei @joshLei5
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Felipe Vaca @felipevaca
129 Followers 552 Following PhD in biomedical sciences. Working in Oncogenomics and molecular biology of cancer.
Kai Beattie @KaiABeattie
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Devin Bendixsen, PhD @DevinBendixsen
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DavidHanson777 @DavidHanson777
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Matthew Abikenari @Matthewabii
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biswanath chowdhury @biswa2410
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Zunairah Shah @ZunairahShah
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roula kitosou @RKitosou
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Jackson Weir @jacksonweir4
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VisionaryEllaTaylor @jL62zi76fVS8l
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Hieu Nguyen @NhmhHieu
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Laith @qtlobga
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Waggoner Lab @LabWaggoner
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Ruidong Xue @riddle_xue
56 Followers 407 Following PhD. Cancer genomics, tumour evolution, and single cell genomics. Particually for liver cancer.
Rui Ye @RuiYejerry
128 Followers 556 Following PhD candidate at GSBS MDACC. Interested in single-cell genomics, and its application in cancer evolution and therapeutic resistance.
Yipeng Xie @YipengXieutsw
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長崎大学 統合... @nMoJoTnzP827353
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周盛 @qi8GkXTyFif5cPH
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Nilabja Bhattacharjee @NilabjaBhattac3
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Matthew Morrison @MMorrisonBioSci
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Somaieh Hedayat @Somaieh_Hedayat
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Pravin Velmurugan @PravinVel98
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Peinan Zhaop @PeinanZhaop
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Giacomo Corleone @Corleojack
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Tnvyr. @compbio_
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Angeles Mercedes Ovie... @AngelesMOviedo
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Huw Rees @Huw_Rees_
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Kartiksachdeva @Kartiksachdeva_
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Jun | Relationship & ... @UmutDisel
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JNP @jnpant
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Allison Rosen, MS @ARosen380
3K Followers 4K Following #Cancer survivor, patient #advocate, Public #speaker, @AmericanCancer Director Project ECHO, @MDAndersonNews @SWOG volunteer. #crcsm #ayacsm Views my own
Andrew Dhawan @andrewdhawan
1K Followers 3K Following Neuro-onc @CleClinicMD |🧠ologist | DPhil @UniofOxford | MD @queensu | Math @uwaterloo | #neuro #onc #genomics #math | https://t.co/2tEFhBANYr | he/him
Julia Belk @juliabelk
188 Followers 365 Following immunology, stem cells, aging HHMI Hanna Gray Fellow @StanfordMed previously @StanfordEng @MITEECS
Pauline L. Pfuderer @PaulinePfuderer
223 Followers 612 Following PhD Student @Cambridge_Uni & @CRUKCamCentre engineering AI 🤖 for biology 🧬 | 👩🏼🔬 previously @harvardmed @embl @DKFZ @iGEMHeidelberg
Luisa Sánchez Lorenz... @LuisaSnchezLor1
130 Followers 188 Following
Dr. María D. Mayán @MariaDMayan
5K Followers 4K Following Aging & Cancer. Connexins | Research Group Leader at @cinbio_uvigo | PI Horizon Europe consortiums | @uvigo | Committed to Women in Science and Equity
Leo Volkov @volkov_leo
145 Followers 582 Following Postdoc at the Yoshimatsu lab at WashU. Previous PhD student in the Corbo lab. Fishing for answers about retinal development. 🐟
Michelle Monje 🟦 @michelle_monje
20K Followers 2K Following Neuroscientist. Neuro-oncologist. Mom. @Stanford @HHMInews @CancerNeurosci. (Opinions are my own and do not reflect those of my employer)
Itai Yanai @ItaiYanai
34K Followers 2K Following Professor at the NYU School of Medicine. Co-host of the 'Night Science Podcast' @nightsciencepod and Co-founder of the Night Science Institute https://t.co/lede3rBmXU
King L Hung @kinglhung
1K Followers 157 Following Biologist at Scripps, PhD at Stanford. Dynamics of genomes and cells.
Mariella Filbin @FilbinMariella
4K Followers 611 Following pediatric neurooncologist and physician scientist, passionate about finding new treatments for pediatric brain cancer @dfbc_pedcare @danafarber @bostonchildrens
Dan Landau @landau_lab
12K Followers 3K Following Somatic evolution, cancer genomics, epigenomics (Weill Cornell/New York Genome Center). Hemato-oncologist (NYP). Discl.: https://t.co/7TBNcbcVCP
Elizabeth McKenna @ElizSMcKenna
19K Followers 5K Following Executive Editor of Cancer Discovery @CD_AACR, published by @AACR. @BBS_Harvard/@DanaFarber alum. Native New Yorker. Views/likes/RTs are my own. She/her
Cancer Discovery @CD_AACR
23K Followers 228 Following Follow Cancer Discovery for high-impact articles and news covering major advances in basic, translational, and clinical cancer research. Published by @AACR.
Nature Genetics @NatureGenet
127K Followers 1K Following Nature Genetics is a monthly journal publishing high impact research in genetics and genomics. RT/like=interesting/relevant, not necessarily endorsement.
Cancer Cell @Cancer_Cell
75K Followers 300 Following Cancer Cell provides a high-profile forum for showcasing advances in cancer research, with a strong emphasis on translational research.
Anton Henssen @anton_gh
1K Followers 1K Following Head of preclinical pediatric cancer research @ChariteBerlin ECRC @MDC_Berlin. Extrachromosomal DNA (ecDNA) in cancer. Cancer Grand Challenges Team eDyNAmiC
Harmit S. Malik @HarmitMalik
43K Followers 7K Following Study genetic conflicts professionally. Try to avoid conflicts in personal life (with mixed results). @HutchBasicSci @fredhutch @HHMINEWS He/him
Long Lab @longlabstanford
3K Followers 928 Following Affiliated with @StanfordPath and @Stanford_ChemH. We study mammalian energy metabolism!
SNO @NeuroOnc
11K Followers 471 Following A multidisciplinary society of healthcare professionals dedicated to promoting advances in neuro-oncology through research and education.
Nature Cancer @NatureCancer
39K Followers 370 Following Nature Cancer is a journal dedicated to publishing the latest advances across all areas of cancer research.
Ash Alizadeh, MD/PhD ... @AshAlizadeh
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Vennetilab @vennetilab
1K Followers 305 Following The Venneti lab's goal is to develop cures for DIPGs and childhood ependymomas.
Julien Sage @SageJulien
2K Followers 412 Following
Charles Swanton @CharlesSwanton
16K Followers 829 Following Cancer Evolution and Genome Instability, Lung Oncologist Air Pollution and Drug Resistance Fair Weather 🚴
Samuel Bakhoum @Samuel_Bakhoum
3K Followers 1K Following #Physician_Scientist interested in #Chromosomal_Instability, #aneuploidy, and #cancer views expressed are my own
Connor Frey @connorfreyy
170 Followers 579 Following UBC Internal Medicine PGY1 | Alum @UBCMedicine | Researcher at @BCCancer | Interested in the role of genomics in cancer and immunotherapy | Vancouver, BC 🇨🇦
Vladas Oleinikovas, P... @OleinikovasV
442 Followers 818 Following Computational Chemist - CADD/TPD; PhD Chemistry at UCL; BA, MSci Natural Sciences, Chemistry (Cantab). @OleinikovasV.bsky.social
Kim Hanssen @KimHanssen1
390 Followers 763 Following Postdoc @GrunewaldLab @DKFZ @KiTZ_HD | @AvHStiftung Fellow | Sarcoma, Neuroblastoma, Metabolism, Drug Resistance | 🇦🇺Aussie abroad🇩🇪 (She/her, views my own)
M. Ammar Haider @gliomah
448 Followers 2K Following Neurosurgery + Sci-Fi Aficionado | IMG 📍Bay Area
Yuvaan Tiwari Foundat... @YuvaanTiwari
569 Followers 718 Following In memory of our 3-year-old son and hero Yuvi, we fund research to accelerate a cure for DMG/DIPG & other fatal pediatric brain tumors. #EndPediatricBrainCancer
Khalil Ali Ahmad @KhalilRajeh3
59 Followers 336 Following Pharmacologist| Cancer Neuroscientist|Pain Researcher @MDAndersonNews
Nick Vitanza @VitanzaNick
6K Followers 1K Following pediatric neuro-oncologist & scientist // #VitanzaLab focusing on #DIPG #DMG #CNStumors & #CARTcell immunotherapy @seattlechildren @UWmedicine
Erik Marchese @erikjmarchese
5 Followers 57 Following
Weisi Liu @weisi_liu
83 Followers 169 Following Translational Medicine Scientist at Burning Rock. Trained in Dr. Bishoy Faltas lab at WCM.
Yujin Suk @suk_yujin
357 Followers 951 Following MD/PhD Candidate @mcmasteru studying immunotherapy in pediatric brain cancer 🧠 💉 raising landshark/husky during incubation time
Myung-Jun Ko, MD PhD @MJKo_MDPhD
615 Followers 635 Following Neurosurgery Resident PGY-1 @CCFFLNeuro / Surgical Internship @UCLASurgeryRes / MD @dgsomUCLA / PhD @HopkinsMedicine / BS @UHmanoa 🇰🇷🇺🇸🌎
Dr. Ananta Gorai @Dr_Ananta_Gorai
47 Followers 131 Following #Founder @ ClinSync ACE WEC Member ex-@NUSBizSchool Mentor PhD @iacskolkata #Oncology #Clinical Trial
Yilin Xu @YilinXu_22
4 Followers 37 Following
Fanis Michailidis @FNMichailidis
81 Followers 198 Following
Marta Barniol-Xicota @mbarniolx
278 Followers 650 Following currently in bluesky. Assistant Prof @UPFbiomed. Junior Leader Fellow @BecariosFLC. Postdoc @mbogyo & @verhelstlab. Enzymes & things in membranes.
Marcos Díaz-Gay @mdiazgay
237 Followers 722 Following Junior Group Leader at @CNIOStopCancer | Postdoc at Alexandrov lab @UCSanDiego | PhD, Medicine and Translational Research @OGIPclinic/@UniBarcelona
Marta Pineda @MartaPinedaRiu
121 Followers 135 Following Investigator - DNA MisMatch Repair team | Hereditary Cancer Program @idibell_cat @ICO_oncologia | Hereditary cancer, Lynch syndorme, CMMRD, genetic diagnostics
Bruno Beernaert @BrunoBeernaert
244 Followers 809 Following DPhil Cancer Science (@CR_UK) Candidate at @UniofOxford | Innate tumour immunology in @ParkesLab
Gemma Alderton @AldertonBiol
2K Followers 2K Following After 18 years at top tier journals, I am now consulting as a freelance editor/writer for researchers in biological sciences at biosciedit. Get in touch!
Adrià Cañellas Soci... @adriacanyellas
731 Followers 1K Following Postdoc in cellular therapies and synthetic biology @MackallLab @StanfordMed | Alumni @Batllelab @IRBBarcelona | Mallorquí
Sarina Shabso @SarinaShabso
222 Followers 358 Following 👩🏻🔬 Postdoc @TheCleversLab @_hubrecht Liver organoids, plasticity and disease modeling | 🦋@sarinashabso.bsky.social
Hunter Bennett @hbennett_mdphd
119 Followers 158 Following Fellow Stanford Hem/Onc& Stanford TIP Interested in Transcription, Innate Immunity, & Oncology Surfer of waist-high waves
Selin Kolsuz, MD @selinkolsuz25
37 Followers 207 Following Postdoc @ MD Anderson Cancer Center - Lymphoma/Myeloma Department #MakeCancerHistory
Bella Reichmann @BellaSteve666
54 Followers 2K Following Entrepreneur, financier, and currently committed to being a philanthropist. “Those who are happiest are those who do the most for others. “
Bruno Melillo @brumelillo
189 Followers 601 Following
Tommy West @TommyWest54
18 Followers 69 Following
Justin Engel @JustinEngel17
240 Followers 458 Following Postdoctoral Fellow at Astrazeneca // PhD at UT Southwestern // views are my own
Demi Sandel @DemiSandel
888 Followers 998 Following Postdoc @UCSF in the labs of @r_rutishauser and @spitzerlab | Previously @labjacks and @newmanlatech
Thaidy @ThayMoRo
348 Followers 1K Following Postdoctoral scholar at @UCSF studying PCa evolution in response to targeted therapy | Molecular biologist & genomics | (she/her) | @[email protected]
Amanda Mennie MD PhD @AmandaMennie
298 Followers 654 Following Onc Fellow @peterlylab @utswinternalmed @utswhemeonc MD, PhD @torunakamuralabuic @uicmstp @uiccom 2020||
Ruth Brennan @rbrennan12
596 Followers 3K Following Head of Strategic Relationships Science Operations Wellcome Sanger Institute
Wanying Wu @WanyingWu5
2 Followers 76 Following
Reese Caldwell @reesecald
131 Followers 382 Following PhD Student in @LiuGroup, @BroadInstitute, @BBS_Harvard | genome editing and RNA
Bailee Sliker, Ph.D @DrBaileeSliker
2K Followers 3K Following Oncology Scientist/Medical Writer at @NCCN. Previously at @CD_AACR. Trained at @FoxChaseCancer and @unmc. Avid long distance runner. Views are my own.
Faiz Jabbar @faizjab
166 Followers 1K Following Clinical Radiology Trainee @KingsCollegeNHS & Normal tissue evolution @TheCrick @SwantonLab | @OxfordMedsci AFP | @UCLMS alum
Shuke Xiao 肖舒克 @Shuke_Xiao
282 Followers 773 Following K99/R00 Postdoc fellow: @longlabstanford @StanfordPath @Stanford_ChEMH PhD: @CarlsonLab_Yale #FirstGen
yx驾到 @VlXBvPyA9cmisY2
2 Followers 150 Following
Yunfeng Lin @LinYunfeng1985
22 Followers 69 Following Research Assistant Professor 1. Cell and Molecular Biologist. Research on DNA Damage Response/Repair. 2. Nano Chemist. 3. Photographer. 4. Computer Programmer.
Joy Elise @JoyElise1998
39 Followers 2K Following
Emanuela Volpi @emanuela_volpi
581 Followers 1K Following Professor, University of Westminster. Genetics, Genomics and Microscopy. Genome-environment interactions and human health 🧬🔬🩺Opinions are my own.
YUQING YANG @YUQINGY28476352
3 Followers 29 Following
Kirit Singh @KiritSingh
156 Followers 629 Following Immuno-engineering @AdaptinBio @prtbtcatduke MD, PhD @QMULBartsTheLon @DukeUBME 🇬🇧 in 🇺🇸
Benjamin Olshin @BenjaminOlshin
70 Followers 940 Following Behavioral science, global impact, social entrepreneurship & innovation through scale. Econ + Cog Neuro @WUSTL. Ex-RA @BehaviorChange
Bella Wilson @beltdseww
59 Followers 2K Following Believer, Philanthropy, Entrepreneur, Web30, buddhist|Food lover, comments are entirely my own, not a robot
Brett Taylor @brettmaxtaylor
181 Followers 518 Following @ucsd_mstp G4 in @FurnariLab and Bing Ren’s lab studying cell identity and ecDNA in glioblastoma. Interested in neuro-oncology & palliative care.
Emil Larsson @snartgubbe
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